NEJM: the value of Genome Wide Association Studies 16 Apr 2009

This week, the New England Journal of Medicine has published on Genome Wide Association Studies.  A Review article summarises the progress made over recent years.  Two Perspective articles contemplate these studies' usefulness.  One argues that the SNPs uncovered by these studies do not have enough relevance to be useful clinical predictors in medicine today.  Another commentator argues that this is not the point - GWAS are uncovering new biological pathways for disease.  Most involved in the online debate agree that full sequencing studies are needed to truly understand the genetic basis of common disease.