Publications
The following publications have been generated by Oxford Nanopore Technologies or our academic collaborators. If you would like to be kept informed of future developments please click here to receive news alerts.
Publications related to sequencing DNA
'Strand sequencing'
Processive replication of single DNA molecules in a nanopore catalyzed by ph29 DNA polymerase. J. Am. Chem. Soc. 132 (50), 17961-72 (2010)
Identification of epigenetic DNA modifications with a protein nanopore. Chem. Commun. 46 (43), 8195-8197 (2010)
Replication of individual DNA molecules under electronic control using a protein nanopore.
Nat. Nanotechnol. 5 (11), 798-806 (2010)
Nucleobase recognition in ssDNA at the central constriction of the alpha hemolysin pore. Nano Lett. 10 (9), 3633-3637 (2010)
Multiple base recognition sites in a biological nanopore: two heads are better than one. Angew. Chem. Int. Ed. 49 (3), 556-559 (2010)
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore. PNAS 106 (19), 7702-7707 (2009)
Sequence-specific detection of individual DNA strands using engineered nanopores. Nat. Biotechnol. 19 (7), 636-639 (2001)
'Exonuclease sequencing'
Continuous base identification for single-molecule nanopore DNA sequencing. Nat. Nanotechnol. 4 (4), 265-270 (2009)
Toward single molecule DNA sequencing. J. Am. Chem. Soc. 128 (5), 1705-1710 (2006)
Publications related to nanopores as biosensors
Single molecule detection of nitrogen mustards by covalent reaction within a protein nanopore. J. Am. Chem. Soc. 130 (21), 6813-6819 (2008)
Protein Nanopores with covalently attached molecular adapters. J. Am. Chem. Soc. 129 (151), 16142-16148 (2007)
Direct transfer of membrane proteins from bacteria to planar bilayers for rapid screening by single-channel recording. Nat. Chem. Biol. 2 (6), 314-318 (2006)
Stochastic sensing of enantiomers. J. Am. Chem. Soc. 128 (33), 10684-10685 (2006)
A genetically encoded pore for the stochastic detection of a protein kinase. Chem. BioChem. 7 (12), 1923-1927 (2006)
Direct introduction of single protein channels and pores into lipid bilayers. J. Am. Chem. Soc. 127 (18),6502-6503 (2005)
Stochastic detection of monovalent and bivalent protein-ligand interactions. Angew. Chem. Int. Ed. 43 (7), 842-846 (2004)
Stochastic sensing of TNT with a genetically engineered pore. Chem. BioChem 6 (10), 1875-1881 (2005)
Kinetics of a reversible covalent-bond forming reaction observed at the single-molecule level. Angew. Chem. Int. Ed. 41 (19), 3707-3709 (2002)
Capture of a single molecule in a nanocavity. Science 291 (5504), 636-640 (2001)
Publications related to solid-state nanopores
Local electrical potential detection of DNA by nanowire-nanopore sensors. Nat Nanotechnol. doi:10.1038/nnano.2011.217
Hybrid pore formation by directed insertion of alpha hemolysin into solid-state nanopores. Nat. Nanotechnol. 5 (12), 874-877 (2010)
Ice Lithography for Nanodevices. Nano Lett. 10 (12), 5056-5059 (2010)
Graphene as a sub nanometre trans-electrode membrane. Nature 467 (7312), 190-193 (2010) Accompanying
editorial by Professor Hagan Bayley
Recapturing and trapping single molecules with a solid-state nanopore. Nat. Nanotechnol. 2 (12), 775-779 (2007)
DNA conformation and base number simultaneously determined in a nanopore. Electrophoresis 28 (10), 3186-3192 (2007)
Review articles
Solid-state Nanopores Nat. Nanotechnol. 2 (4), 209-215 (2007)
Nanopore analysis of nucleic acids bound to exonucleases. Ann. Rev. Biophys. 39, 79-90 (2010)
The potential and challenges of nanopore sequencing. Nat. Biotechnol. 26 (10), 1146-1153 (2008) Download the article here from
genome.govSequencing single molecules of DNA. Curr. Opin. Chem. Biol. 10 (6), 628-637 (2006)
Stochastic sensors inspired by biology. Nature 413 (6852),226-230 (2001)
Stochastic sensing with protein pores. Adv. Mater. 12 (2), 139-142 (2000)
Building doors into cells. Sci. Am. 277 (3), 62-67 (1997)
