Introduction to nanopore sensing
The GridION™ system
The MinION™ device: a miniaturised sensing system
Analytes and Applications: DNA, RNA, proteins
- DNA: An introduction to nanopore sequencing
- DNA: strand sequencing
- DNA: exonuclease sequencing
- DNA sequencing: applications
- Protein analysis
- Small molecules
Fields of use
Oxford Nanopore is developing two methods of DNA sequencing, both of which are compatible with the Company's GridION™ and MinION™ systems.
- "Strand sequencing" is a technique that passes intact DNA polymers through a protein nanopore, sequencing in real time as the DNA translocates the pore. Oxford Nanopore intends to commercialise this technology independently.
- "Exonuclease sequencing" is a technique that passes individual nucleotides through a protein nanopore, aided by a processive exonuclease enzyme. Oxford Nanopore signed a commercialisation agreement with Illumina for this technology, however commercialisation timelines have not been disclosed.
The following movie is an introduction to nanopore DNA sequencing. For more information please visit the specific pages linked above.