A nanopore is a nano-scale hole. In its devices, Oxford Nanopore passes an ionic current through nanopores and measures the changes in current as biological molecules pass through the nanopore or near it. The information about the change in current can be used to identify that molecule.
GridION™ is a scalable nanopore sensing system that includes individual instruments called nodes, each of which works with a consumable cartridge containing nanopore apparatus. Nodes can be clustered to share information during real time analyses.
PromethION™ is a tablet-sized benchtop instrument for molecular analyses driven by nanopore technology. It is designed to allow the analysis of DNA, RNA, proteins or small molecules.
PromethION™ gives users the choice of how many nanopores are being used for a particular sample; choose from running an individual sample to multiple samples in parallel.
The MinION™ device is a portable nanopore sensor. The MinION Access Programme started in Spring 2014; participants are initially exploring the use of MinION™ in a broad range of applications for DNA sequencing.
Nanopores can be adapted for the analysis of DNA (DNA sequencing)
Nanopores can be adapted for the analysis of RNA. Currently, Oxford Nanopore is exploring direct micro RNA analysis but the system is also being developed for the sequencing of RNA strands.
Nanopores can be adapted for the analysis of proteins.
The MinION and GridION systems are designed so that any user can access nanopore sensing technology, whether they are based in academia or industry and whether they need to perform analyses in a central/lab environment or in the field.
Many people with an interest in Oxford Nanopore systems are based in academic research, for example understanding the structure of various genomes, exploring the impact of the human genome on health or developing techniques for better analysis of biological systems.
Many people with an interest in Oxford Nanopore systems wish to explore industrial research and applications, for example monitoring food safety throughout a food chain or distribution network, understanding healthcare implications of biological information or using biological markers to track supplies of timber or other products.