Oxford Nanopore Technologies Ltd

MinION is a pocket-sized portable device used for real-time biological analysis. It is adaptable to the analysis of DNA, RNA, or proteins. MinION's simple workflow allows end-to-end experiments in many environments.

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PromethION combines MinION's simplicity of use with greater workflow flexibility through scale and a modular design. Increase throughput by analysing the same sample simultaneously in multiple flow cells, or run different samples concurrently.

The GridION system, currently in development, is a scalable real-time analysis system designed to analyse single molecules such as DNA, RNA and proteins.

Metrichor provides a cloud-based platform for real time analysis of data from nanopore devices. Applications available through Metrichor will expand with the ultimate goal of enabling the analysis of any living thing, by any user, in any environment.

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MinION

Portable, real-time biological analyses

MinION is a portable device for molecular analyses that is driven by nanopore technology. It is adaptable for the analysis of DNA, RNA, proteins or small molecules with a straightforward workflow. The MinION product specification is available here.

More about sequencing with MinION

Scalability

The MinION can be run for minutes or days according to the experimental need. Users can adjust settings like the speed that the DNA passes through the nanopore. PromethION, which will soon be released into early access, is designed to be fully scalable so that users can operate between one or 48 flow cells at any one time.

Long read lengths

The Oxford Nanopore system processes the reads that are presented to it rather than generating specific read lengths. The longest read reported by a MinION user to date is more than 200Kb, but it can process the spectrum of read lengths.

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Real-time data

Nanopore sequencing data starts streaming immediately, rather than being delivered in bulk at the end of a 'run'. The implications of this on workflows and fast turnaround results has been explored in many applications. For example, returning an answer on a species identification very quickly, or allowing sequencing experiments to be stopped if sufficient data has accumulated to answer a question, so you can move on to the next experiment.

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Real-time data

Direct molecular analysis

Nanopore sequencing data starts streaming immediately. Being able to sequence the native DNA/RNA helps to avoid errors introduced by amplification and other preparation procedures. It also has potential uses in the analysis of modified bases.

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Portability

The MinION can be used outside the traditional lab environment to perform field-based work - taking the analysis to the sample. VolTRAX, in development for automated sample prep, will further enable sequencing in diverse environments and by those with fewer lab skills.

Weight:
87g (103g with a flow cell)

Size:
W 105, H 23, D 33mm

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New: Nature publication: “Real-time, portable genome sequencing for Ebola surveillance”

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Simple workflows

Learn about Voltrax

Simple sample preparation (Coming soon: automated sample preparation from Voltrax)

Learn about Voltrax

Learn about MinION

Pocket-sized MinION for analysis anywhere

Learn about MinION

Learn about PromethION

Desktop PromethION for high throughput analysis

Learn about PromethION

Learn about Metrichor

Real time analysis solutions from Metrichor

Learn about Metrichor

About Oxford Nanopore Technologies

Our goal: to enable the analysis of any living thing, by any person, in any environment

Oxford Nanopore Technologies is developing and commercialising a new generation of nanopore-based electronic systems for analysis of single molecules, including DNA, RNA and proteins. The handheld MinION device, the high-throughput/high sample number PromethION and GridION systems are designed to provide novel qualities in molecular sensing such as real-time data streaming, improved simplicity, efficiency and scalability of workflows and direct analysis of the molecule of interest...

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The devices may be used in scientific research, personalised medicine, crop science, security and defence and environmental applications

Oxford Nanopore is developing or providing products and services to simplify all parts of the nanopore-based molecular analysis workflow. For sample preparation this includes VolTRAX, a rapid, programmable, portable, disposable sample preparation device designed to convert complex samples such as blood, saliva or environmental samples directly onto a nanopore sensing device. For analysis this includes Metrichor, a cloud based service for real time molecular analyses, vertically integrated with nanopore sensing devices. MinION is commercially available and registration has opened for the PromethION Early Access programme (PEAP). Supported by a broad patent portfolio, the Oxford Nanopore pipeline includes multiple generations of nanopore-based sensing technologies, including those based on both biological and solid-state nanopores.

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